Jacob’s Ladder: The History of the Human Genome

By Henry Gee

In ‘Deep Time’ Henry Gee told us why the chicken came before the egg. In his new book, ‘Jacob’s Ladder’, he tells us the comprehensive answer to the simple question: how did I get here?

When the human genome was unveiled on 12 February 2001, headlines were filled with announcements that we had found the genes which cause schizophrenia, homosexuality and more. The assumption was that the genome offered a blueprint for what made human beings: the reality is far more complex and significant.

The true importance of our discovery of the engine of life is that it offers us the possibility of altering our evolutionary destiny. Biology, once a passive science of observation, now possesses the tools to create form from the formless. For the first time we have the opportunity to shape life; like the angels on Jacob’s Ladder, we are poised on the brink of godlike powers. But as Gee powerfully argues, we must exercise these powers with caution and learn from the mistakes of the past. He traces the entertaining history of man’s search for what brings form from the formless, revealing the extraordinary thinkers and often bizarre experiments that led to this epochal moment: from Aristotle’s musings and zany experiments with frogs and taffeta trousers which proved that sperm fertilised eggs, through the insights of poet scientists such as Goethe, to Darwin and the eventual discovery of the genome. Not only does the genome show us how each individual is created, but it reveals the evolutionary history of all species, telling the story of mankind’s survival against the odds.

This provocative and accessible book investigates the latest and most radical discoveries about what makes us human. In so doing, it uncovers processes that have only recently been suspected, and never before understood.

Author: Henry Gee
Format: Hardback
Release Date: 01 Mar 2004
Pages: 288
ISBN: 978-1-84115-734-4
Henry Gee is the chief science writer and assistant editor of Nature. He holds a PhD from Cambridge in Zoology and has previously been Regent’s Professor at UCLA. He also contributes to Le Monde, El Pais, Die Zeit and has previously written Before the Backbone: Views on the Origin of the Vertebrates (1996) and Deep Time, which is also published by Fourth Estate.

Praise for ‘On Deep Time’: -

”'This book will surprise, outrage and delight you - and make you think.” - Jared Diamond

”'Gee takes the reader inside contemporary palaeontology, from the excitement of a fossil dig with Maeve Leakey to the thousands of carefully stored and catalogued specimens at the Natural History Museum.” - New Scientist

”'As Gee’s brilliant analysis shows, viewed afresh, evolution proves a more interesting and exciting - if more complex - story than we ever thought.” - Scotsman